Case Study No.3

Case Study No.3

Patient Male ‘SP’ Born 1970

This patient came to the clinic complaining on pain in the legs at rest and while working, dryness of the mouth, frequency of urination at night.

From anamnesis:

The patient was diagnosed with diabetes in 2005 and obesity (100kg weight, height 180cms). At this time he complained of dryness in the mouth and blood glucose levels of 18.0 mmol/l. The patient was recommended insulin therapy/ HbA1c and micro-albumin tests were not carried out. He also was not seen by either a podiatrist or an ophthalmologist.

Treatment

On arrival in the clinic the patient was being treated with intensive insulin therapy by frequent injections of Aktrapid 10 units p/z, 12 units p/o, 10 units p/u; Lantus 18 units mornings. He had come to the clinic seeking further investigation and treatment. The following laboratory analyses were made:


Testresultnormal range
ALT200-41 units/l
AST150-38 units/l
Gamma-GT24М.12-64 units/l
Glucose13,84 3,9-6,0 Mmol
Urea7,02,5-9,2 Mmol/l
Creatinine8953-115 Mmol/l
Cholesterol Total4,060-5,17 Mmol/l
Cholesterol HDL1,120,9-1,68 Mmol/l
Cholesterol LDL3,091,9-4,14 Mmol/l
Glycated Hemoglobin14,34,8-6,0%
C-Peptid614,012298-1324 pmol/l

C-Peptid298-1324 pmol/l1180,352

Blood Analysis for infections made on 05.08.2006

TestResultNormal
Chlamydia trachomatis IgG11,1>1,1 positive<0,9 negative0,9-1,1 grey area
CMV IgG19,698<0,5 МЕ/ml negative=0,5-0,7 МЕ/ml doubtful>0,7 МЕ/мл positive
Chlamydia  pneum. lgApresentNot present
Chlamydia  pneum. lgG11,19-11 grey zone>11 positive


Smear Tests for infection made on 05.08.2006

TestResultdefault span
default spandefault spandefault span
default spandefault spandefault span
default spanPresentNot present
Colour duplex scanning of the arteries of the lower limbs.

1. The ‘intima-media’ complex of both femoral arteries – no thickening (up to 1.0mm, (normal range up to 1.2mm) ; Intima condensed.

The walls of the mouths and proximal divisions of the deep femoral arteries are not thickened or condensed.

The walls of the upper femoral and popliteal arteries are not thickened or condensed. Blood supply is unchanged in the major, general, deep and superficial arteries.

2. The walls of the rear and front tibial arteries and the arteries of the feet are not thickened or condensed.

Results

Following a full analysis of the patient’s results we carried out systematic treatment in order to act on all the elements of the pathogenesis of his illness (insulin resistance, hyper production of glucose, glucose toxicity) and also treated his infections. All the above enabled the patient to stop insulin therapy and change to an oral sugar reducing prescription.

In order to check the results of this treatment, control checks were made of the main clinical/laboratory analyses: НвА1 dropped twofold to 8,3% (normal 4-6 %), the patient felt much better generally and had lost the sensation of a dry moth and pain in his legs. He also lost 8 kgs in weight bringing his BMI down to 28 (Kg/M2).

Conclusion

Summarising in brief these results, we have come to the conclusion that we have established an optimal type of treatment for patients with diabetes, enabling them to improve their metabolism of carbohydrates which significantly reduces the risk of further complications.